LymphedemaV1, Main, Exploration, bibRecord, 00DD91

[A study of ivermectin in the treatment of lymphatic filariasis due to Wuchereria bancrofti var. pacifica in French Polynesia].

Identifieur interne : 00DD91 ( Main/Exploration ); précédent : 00DD90; suivant : 00DD92

[A study of ivermectin in the treatment of lymphatic filariasis due to Wuchereria bancrofti var. pacifica in French Polynesia].

Auteurs : J. Roux ; P. Perolat ; J L Cartel ; J P Boutin ; Y. Sechan ; M. Larivière ; M A Aziz

Source :

Bulletin de la Societe de pathologie exotique et de ses filiales ; 1989.

RBID : pubmed:2743520

Descripteurs français

KwdFr :
- Adulte, Animaux, Filariose lymphatique (traitement médicamenteux), Filarioses (traitement médicamenteux), Humains, Ivermectine (effets indésirables), Ivermectine (usage thérapeutique), Mâle, Polynésie, Porteur sain (traitement médicamenteux), Wuchereria.
MESH :
- effets indésirables : Ivermectine.
- traitement médicamenteux : Filariose lymphatique, Filarioses, Porteur sain.
- usage thérapeutique : Ivermectine.
- Adulte, Animaux, Humains, Mâle, Polynésie, Wuchereria.

English descriptors

KwdEn :
- Adult, Animals, Carrier State (drug therapy), Elephantiasis, Filarial (drug therapy), Filariasis (drug therapy), Humans, Ivermectin (adverse effects), Ivermectin (therapeutic use), Male, Polynesia, Wuchereria.
MESH :
- chemical , adverse effects : Ivermectin.
- geographic : Polynesia.
- drug therapy : Carrier State, Elephantiasis, Filarial, Filariasis.
- chemical , therapeutic use : Ivermectin.
- Adult, Animals, Humans, Male, Wuchereria.

Abstract

Forty carriers of 20 or more W. bancrofti var. pacifica per ml were blind administered ivermectin at 50, 100, 150 or 200 mcg/kg doses. The rate of successful treatment was 100% with the 4 dosages. The percentage cure rate and the decrease percentage in the microfilarial count were significantly higher in persons treated with 100, 150 and 200 mcg/kg than in persons treated with 50 mcg/kg. Frequency and intensity of side-reactions were similar to those observed during treatment with DEC; they were more frequent and severe in persons with greatest microfilaremia but did not depend on the dosage. Ivermectin in 100 mcg/kg single-dose, administered once a year, is the best candidate to replace DEC in mass treatments.

PubMed: 2743520

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en">Forty carriers of 20 or more W. bancrofti var. pacifica per ml were blind administered ivermectin at 50, 100, 150 or 200 mcg/kg doses. The rate of successful treatment was 100% with the 4 dosages. The percentage cure rate and the decrease percentage in the microfilarial count were significantly higher in persons treated with 100, 150 and 200 mcg/kg than in persons treated with 50 mcg/kg. Frequency and intensity of side-reactions were similar to those observed during treatment with DEC; they were more frequent and severe in persons with greatest microfilaremia but did not depend on the dosage. Ivermectin in 100 mcg/kg single-dose, administered once a year, is the best candidate to replace DEC in mass treatments.</div>
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Serveur d'exploration sur le lymphœdème

[A study of ivermectin in the treatment of lymphatic filariasis due to Wuchereria bancrofti var. pacifica in French Polynesia].

[A study of ivermectin in the treatment of lymphatic filariasis due to Wuchereria bancrofti var. pacifica in French Polynesia].

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

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